컨텐츠 시작
학술대회/행사
초록검색
| 제출번호(No.) | 0214 |
|---|---|
| 분류(Section) | Poster Session |
| 분과(Session) | (AM) Applied Mathematics(including AI, Data Science) (AM) |
| 발표시간(Time) | 19th-B-14:00 -- 14:30 |
| 영문제목 (Title(Eng.)) |
Beyond homogeneity: Assessing the validity of the Michaelis-Menten rate law in spatially heterogeneous environments |
| 저자(Author(s)) |
Seolah Shin1, Seok Joo Chae2, Seunggyu Lee1, Jae Kyoung Kim2 Korea University1, KAIST2 |
| 초록본문(Abstract) | The Michaelis-Menten (MM) rate law has been widely used to describe enzyme-catalyzed reactions for over a century. While the applicability of the MM rate law is easily assessed in homogeneous environments, determining its applicability in heterogeneous environments, which are common in biological systems, poses challenges. This study shows that the MM rate law can yield misleading results under spatial heterogeneity. To address this issue, we propose an alternative method suitable for spatially heterogeneous environments. |
| 분류기호 (MSC number(s)) |
35-90 |
| 키워드(Keyword(s)) | QSSA, PDE, validity condition |
| 강연 형태 (Language of Session (Talk)) |
English |